The best Airbnbs in the Midwest range from treehouses and cabins rentals on lakes to luxury vacation rentals in cities. From group trips and family reunions to romantic retreats tucked in nature, there’s truly something for everyone in this neck of the woods. Just wait until you see these Midwest vacation rentals on Airbnb and VRBO.
Also known as the American Heartland, the Midwest is one of the coolest regions in the US. It’s comprised of 12 states, each offering some amazing Midwest vacation rentals. These unique stays provide a safer and more authentic experience than traditional hotels, making them especially desirable in the age of COVID.
If you’re looking for a relaxing Midwestern getaway this summer of fall, you’re in luck. This article covers the top lodging in the Midwest, encompassing Airbnbs, VRBOs, and cabins for rent in the Midwest.
Here, we’ve ranked the best Airbnbs in the Midwest, which include the following states: Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Nebraska, North Dakota, Ohio, South Dakota, and Wisconsin. Without further ado, let’s explore the Midwest!
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The Coolest Airbnbs in the Midwest: Top Vacation Rentals in 2021
Here are the best Airbnbs in the Midwest by category, taking into account different amenities, trip types, and budgets. The subsequent sections will cover each listing in more detail.
Top Airbnb in the Midwest: Frank Lloyd Wright’s The Meyer House
Best Luxury Vacation Rental Midwest: Luxe Cabin for Large Groups
Top Romantic Airbnb in the Midwest: Quiet Lakefront Cottage with Dock
Best Midwest Airbnb for Large Groups: Unique Barn Rental
Best Cheap Vacation Rental in Midwest: Lakefront Log Cabin in Michigan
Coolest Treehouse Airbnb in the Midwest: Romantic Treehouse Getaway
Best Cabin Rental Midwest: Cozy Pines Rental with Hot Tub
Top Airbnb Midwest with Pool: Beautiful Family Home Near Lake Michigan
Best Winter Vacation Rental Midwest: Boyne Mountain Villa Condo
Best Lake House Rental Midwest: Lake Superior Top Vacation Rental
Most Unique Airbnb in the Midwest: Treehouse Rental Yurt in the Wilderness
17 Best Airbnbs in the Midwest
If cabins, treehouses, romantic cottages, and luxury rentals all sound good to you, get excited! Below are some of the most unique stays in the Midwest:
1. Frank Lloyd Wright’s Schwartz House
Location: Two Rivers, Wisconsin
Rates from: $449 per night
Accommodates: 6 guests
This is one of the most unique buildings, let alone Airbnbs, in the Midwest. Designed by the famous American architecture Frank Lloyd Wright, this beautiful accommodation has been carefully restored to its former splendor. It’s probably one of the most tranquil, peaceful, and aesthetically pleasing spaces imaginable, which is why it deserves to be mentioned among the top Airbnbs in the Midwest!
No availability on your selected dates? Try this Frank Lloyd Wright home in Michigan!
2. Beautiful Lake House Rental Midwest on Lake Geneva – Top Midwest Vacation Rental with Private Pool
Location: Lake Geneva, Wisconsin
Rates from: $1,083 per night
Accommodates: 10 guests
Looking for the perfect Airbnb retreat in Wisconsin? This vacation rental in the Midwest with a private outdoor pool is it!
This 4-story lake house overlooks the crystal clear water of Lake Geneva. It’s decked out with all the amenities you’ll need for a large group stay, including an outdoor pool, gym, sauna and steam shower, wine cellar, 3 fireplaces, a pier, pool table, arcade. What more could you want in one of the best Airbnbs in the Midwest?
In addition to being a top vacation rental in the Midwest, it’s also among the coolest in the world!
3. Secluded A-Frame Cottage – Among the Best Romantic Airbnbs in the Midwest
Location: Innsbruck, Missouri
Rates from: $252 per night
Accommodates: 8 guests
If a romantic A-frame cabin on a lake sounds good to you, definitely check out this beautiful vacation rental in Missouri. It’s one of the most romantic cabins for rent in the Midwest for its idyllic lakeside setting, cozy amenities, and privacy. Soak in the lake views from the large deck, relax on the hammock, and let all of life’s worries go away. This rustic Midwest family vacation rental will blow your mind!
Dreaming of a beautiful lake vacation in Missouri? Read next: Best Airbnbs in Lake of the Ozarks
4. Downtown Fargo Loft Experience – One of the Best Midwest Vacation Rentals
Location: Fargo, North Dakota
Rates from: $119 per night
Accommodates: 4 guests
Looking for a unique Midwest house to rent? This cozy loft in North Dakota is calling your name!
Get inspired by the modern finishings and sleek Scandinavian designs. Take advantage of the 25 ft. lofted ceilings and skylight. You’ll be within walking distance of downtown. However, after stepping foot inside this top Midwest rental, it will be hard to leave!
In addition to being one of the most budget-friendly accommodations on Airbnb and VRBO in the Midwest, it’s also among the few that’s pet friendly!
Read next: Cool Penthouse Lofts across America
5. Decadent Converted Barn – Coolest Airbnb in the Midwest for Large Groups
Location: Pomona, Illinois
Rates from: $369 per night
Accommodates: 16 guests
This unique vacation rental in Illinois offers over 70 acres of fun, perfect for group trips like family reunions, work outings, and other group trips. This barn is considered one of the top stays in the Midwest, and it’s easy to see why.
Converted from a traditional barn into an architecturally unique space, this quintessentially Midwest Airbnb is decked out with tasteful décor and panoramic forest views. From the cozy furniture and amenities to the peaceful acreage and creek surrounding the property, this has to be one of the best Airbnbs in the Midwest for large groups.
6. Crosslake Treetop Bears Den – Among the Best Treehouse Rentals in the Midwest
Location: Crosslake, Minnesota
Rates from: $122 per night
Accommodates: 6 guests
This two-story treehouse is one of the best cabins for rent in Midwest, hands down. It was recently built and offers all the cozy amenities you’ll need for a romantic and memorable stay.
The open floor plan and warm fireplace makes this Midwest vacation rental incredibly unique. From the elevated ground, you can catch a glimpse of wildlife as well as sunrises and sunsets. If you’re looking for a Midwest rental like no other, this one in MN has got you covered!
7. Lakefront Log Cabin – One of the Best Cheap Airbnbs in the Midwest
Location: West Branch, Michigan
Rates from: $82 per night
Accommodates: 4 guests
This log cabin in Michigan is one of the best budget-friendly Airbnbs in the Midwest. It fits 4, has all the amenities you’d expect in a cozy lake house, and offers sweeping views of the lake. With so much to see and do around the property, it’s no wonder this is among the most unique cabins for rent in the Midwest.
Go fishing, rent a pontoon boat, and catch the sunset from the dock and you’ll see why this is among the coolest Airbnbs in the Midwest.
8. Best Airbnb Treehouse Rental in the Midwest
Location: Millersburg, Ohio
Rates from: $190 per night
Accommodates: 2 guests
Looking to stay at one of the best hidden vacation spots? Wait until you see this!
This one-of-a-kind Airbnb treehouse embodies the best of the Midwest. It’s suspended 22 feet in the air, with beautiful views of the surrounding forest. There’s a wrap-around balcony, hot tub, and rustic furnishings, so you can take advantage of this surreal location. With so much charm and attention to detail, this is easily the best Airbnb treehouse rentals in Ohio and in all of the Midwest!
9. Cozy Cabin Rental in the Midwest with a Hot Tub – A Top VRBO Midwest Tucked in Nature
Location: Columbus, Indiana
Rates from: $290 per night
Accommodates: 8 guests
Experience the Midwest in style from this cozy and romantic cabin in Indiana. It’s nestled on a 9-acre wooded property and definitely gives you the feeling of gemütlichkeit in the winter. It’s a top Airbnb and VRBO in Midwest, and it’s easy to see why. Relax in the hot tub and let go of all of life’s worries. It truly doesn’t get any better than this.
This Airbnb cabin for rent in the Midwest features an outdoor hot tub, fire pit, treehouse, horseshoes, and game room. Say no more!
Read next: Tips for Traveling as a Couple
10. Fernside A-Frame on the Riverfront – One of the Top Cabins for Rent in the Midwest
Location: Indian River, Michigan
Rates from: $340 per night
Accommodates: 4 guests
Looking to stay in a cozy A-Frame cabin in the Midwest? This riverfront home in Michigan has got you covered.
Wake up every morning with lovely views of the Sturgeon River and trees as far as the eye can see. Enjoy the seclusion and privacy as you relax on the Adirondack chairs in the backyard. Wildlife will greet you every day as you sit out on the deck. With so much charm and personality, this cabin is easily one of the best Midwestern rentals you’ll find in Michigan.
11. Beautiful Family Vacation Rental in the Midwest with Private Pool
Location: La Porte, Indiana
Rates from: $410 per night
Accommodates: 16 guests
Looking for a home base for your large group of family or friends? This gorgeous Midwest vacation rental with a heated pool is the perfect match. It’s decked out with more than 4,400 sq. ft. of living space, including a pool, wraparound deck and patio, gas grill, fireplace, trampoline, and a huge backyard for fun activities. It’s also close to Indiana Dunes National Park, South Bend, and premium shopping outlets. There’s something for everyone here, which is why it deserves a spot on the best Airbnbs in the Midwest.
Read next: Coolest Places in the World to Travel with Friends
12. Top Airstream Airbnb and Tiny House in the Midwest
Location: Kansas City, Missouri
Rates from: $225 per night
Accommodates: 2 guests
This airstream tiny house is one of the most unique accommodations imaginable! It’s brimming with vintage charm and is equipped all the modern amenities, including a hot tub, smart TV, AC/heat, and kitchen appliances. The private deck is a huge plus, as are the swinging chairs and patio furniture.
When you step inside this modern airstream Airbnb in the Midwest, you’ll know you’re not in Kansas anymore.
13. Boyne Mountain Winter Airbnb Getaway in the Midwest – A Top Midwestern Rental for Large Parties
Location: Boyne Falls, Michigan
Rates from: $307 per night
Accommodates: 15 guests
As far as mountain getaways go, this is among the best in the Midwest! Located at Boyne Mountain, this Midwestern vacation rental is the perfect place for skiing, hiking, and other outdoor activities. The pool is perfect for the summer, while there’s a hot tub to warm you up in the winter. This unique Airbnb can accommodate upwards of 15 guests, making it one of the best vacation rentals in the Midwest for large groups.
If you’re looking for mountain vibes at a vacation rental in the Midwest, this is it!
Read next: Top Rentals in Michigan
14. Lake House Midwest Vacation Rental on Lake Superior
Location: Grand Marais, Minnesota
Rates from: $662 per night
Accommodates: 12 guests
Dreaming of a beautiful Midwest house to rent for a summer vacation? This luxury lake house rental in the Midwest is nestled on the shores of Lake Superior, one of the Great Lakes in the Midwest.
Enjoy a cup of coffee in the morning with sweeping vistas of this lake, or take a stroll into town and peruse the boutique shops. There’s something for everyone here, which is why it’s among the best Airbnbs in the Midwest USA! In addition to being a top Airbnb, it’s also among the coolest Midwest rentals on VRBO.
Read next: Coolest Beach Houses in the USA
15. Treehouse Yurt in the Wilderness – One of the Coolest Midwestern Rentals Imaginable
Location: South Lawrence, South Dakota
Rates from: $119 per night
Accommodates: 6 guests
Looking for the ultimate Airbnb experience in the Midwest? Check out this treehouse yurt in South Dakota. Modeling the Pacific yurts in Oregon, it’s basically one big bedroom in the pine trees. Stargazing is a must. It won’t take long to realize why it’s among the best Midwestern rentals.
Wake up every morning to the sound of birds chirping with panoramic views of the forest, and you’ll see why this is the top Airbnb in the Midwest amongst outdoorsy types.
16. Floating Luxury Boat Airbnb – Stunning Midwest House Rental on a Lake
Location: East Dubuque, Illinois
Rates from: $175 per night
Accommodates: 12 guests
Looking to stay overnight on the water? This luxury boat and best Midwest Airbnb is the perfect staycation!
This 70-foot houseboat is set on the Mississippi River within reach of many top sights in the area. Swimming is not advised due to the powerful currents, but there are kayak rentals available and plenty of other outdoor adventures. In the winter, you can go skiing at two nearby ski resorts.
In addition to being among the top Airbnbs in the Midwest, it’s also one of the top Airbnbs on a boat in the country!
Read next: Coolest Airbnb Boat Rentals
17. Best Luxury Cabin Rental in Midwest
Location: Wild Rose, Wisconsin
Rates from: $394 per night
Accommodates: 16 guests
This large cabin rental in the Midwest is perfect for family summer vacations. It’s set on Kusel Lake, one of the coolest destinations in all of Wisconsin.
Enjoy the gas fireplace with breathtaking views through the window. Play foosball, take advantage of the wet bar and outdoor hot tub. Spend your afternoons on the lake as you swim, kayak, canoe, rowboat, paddleboard, and more. If you’re looking for the ultimate cabin rental in the Midwest, this lake home for rent is the ideal home base.
Best Places to Stay in the Midwest
Still unsure of where you’d like to stay in the Midwest? Here are my favorite cities, towns, and nature areas where I recommend visiting throughout the Midwest states:
– Top Cities and Towns: Branson, Chicago, Charlevoix, Clear Lake, Columbus, Kansas City, Indianapolis
– Best Cabins and Campgrounds: Hocking Hills (OH), Porcupine Mountains (MI), Door County (WI)
– Coolest State Parks and Recreational Areas: Ludington State Park (MI), Indiana Dunes (IN)
Coolest Airbnbs in the Midwest: Michigan, Wisconsin, Illinois, Ohio, Nebraska + More!
Have you ever stayed in a unique Airbnb or vacation rental in the Midwest region of the US? Let me know in the comments or on Insta, as I’m always excited to add onto this list of the best Airbnbs in the Midwest!
Looking for more outdoor adventure destinations? Check out these places:
– Vermont Vacation Rental Air Bnbs
– Best Airbnbs in Jackson Hole Wyoming
– Coolest Stays in the Berkshires
– Best Airbnb Rentals in the White Mountains of NH
– The Most Unique Airbnbs in New England
