10 Amazing Cities in the Southeast for the Ultimate Work-Life Balance

by Jon Miksis
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The Southeast completely changed my definition of work-life balance. While exploring the region last spring, I discovered what’s possible when your lunch break includes paddleboarding in Charleston’s harbor or grabbing fresh biscuits from Atlanta’s Westside. These cities aren’t just about sweet tea and southern charm anymore.

From creative hubs where tech startups mingle with century-old BBQ joints to the best places in the Southeast where you can actually afford a house with a porch, I’ve found spots that nail that modern Southern lifestyle. Whether you’re dreaming of post-work beach walks in Savannah or want easy access to both mountains and the coast, these cities prove you don’t have to choose between career opportunities and quality of life.

Most Amazing Places to Live in the Southeast

Looking for the coolest things to do in Southeast? Experience the vibrant culture of New Orleans, LA, explore the music scene in Nashville, TN, visit historic landmarks in Atlanta, GA, and immerse yourself in the charm of St. Augustine, FL. Whether you’re interested in history, music, or cuisine, here are the top attractions to visit in the Southeast.

  • Best for Music and Entertainment: Nashville, TN
  • Best for History and Culture: St. Augustine, FL
  • Best for City Living: Atlanta, GA
  • Best for Coastal Living: Charleston, SC
  • Best for Quaint Coastal Vibes: Ocean Springs, MS
  • Best for Tech and Innovation: Huntsville, AL
  • Best for Cultural Diversity: New Orleans, LA
  • Best for Mountain Views and Outdoor Activities: Asheville, NC
  • Best for Food Lovers: Savannah, GA
  • Best for a Thriving Downtown Scene: Greenville, SC
The best places to live in the Southeast right now

1. New Orleans, LA

Few cities in the U.S. have the personality of New Orleans. It’s a place where history, music, and food collide to create an experience like no other. Walk through the French Quarter, and you’ll hear jazz spilling onto the streets while the scent of fresh beignets from Café du Monde fills the air. The city thrives on its vibrant culture, from Mardi Gras parades to Creole and Cajun cuisine that’s second to none.

Living here means immersing yourself in a community that values tradition and celebration. Housing options range from historic shotgun houses to modern apartments in the Warehouse District. While summers are hot and humid, the city’s nightlife and festivals make up for it. With a strong sense of local pride and a cost of living lower than many major cities, New Orleans isn’t just a great place to visit—it’s a one-of-a-kind place to call home.

When choosing a Southeastern destination, New Orleans blends old-world charm with modern comforts for a well-rounded experience.
When choosing a Southeastern destination, New Orleans blends old-world charm with modern comforts for a well-rounded experience.

2. Nashville, TN

If music is the soul of a city, then Nashville is alive and thriving. Known as Music City, it’s home to legendary venues like the Grand Ole Opry and the honky-tonks of Broadway, where live performances fill the air day and night. But there’s more to Nashville than just country music. The city’s neighborhoods each offer a unique vibe—East Nashville is hip and artsy, The Gulch is sleek and modern, and 12 South is packed with boutique shops and top-tier restaurants.

Nashville’s job market is booming, especially in healthcare, tech, and entertainment. With no state income tax, a relatively low cost of living (compared to other major metros), and access to hiking trails and the Cumberland River, it’s a place where both career-driven professionals and creatives can thrive. Whether you’re here for the music, the job opportunities, or the unbeatable hot chicken, Nashville is a city that welcomes you with open arms.

For those considering the Southeast's best cities to live in, Nashville offers more than just entertainment.
For those considering the Southeast’s best cities to live in, Nashville offers more than just entertainment.

3. Atlanta, GA

Atlanta is the kind of city that surprises you. It’s got the fast-paced energy of a major metro, but take a turn down the right street, and you’ll find tree-lined neighborhoods that feel like a small town. Every time I visit, I’m struck by how seamlessly it blends history, culture, and opportunity.

Downtown is a hub of activity, home to the Georgia Aquarium, Centennial Olympic Park, and the buzzing nightlife of Midtown. But venture beyond the skyscrapers, and you’ll find gems like Inman Park, with its historic homes and trendy cafés, or the BeltLine, where locals bike, jog, and pop into breweries along the way. Atlanta’s job market is booming, particularly in tech, film, and business, and with Hartsfield-Jackson being the world’s busiest airport, traveling is a breeze. Whether you’re after career growth, cultural experiences, or just some good Southern comfort food, Atlanta delivers.

Atlanta effortlessly fuses urban living with the South's renowned warmth and hospitality.
Atlanta effortlessly fuses urban living with the South’s renowned warmth and hospitality.

4. St. Augustine, FL

St. Augustine is the kind of place that makes you slow down and appreciate the moment. Maybe it’s the cobblestone streets, the Spanish-style buildings, or the sound of waves crashing on the shore—it just has that timeless charm. As the oldest city in the U.S., history is everywhere, from the Castillo de San Marcos to the charming cafés in historic downtown.

But don’t let its age fool you—St. Augustine is as lively as ever. The local food scene is fantastic (seafood lovers, take note), the beaches are stunning, and there’s always a festival or live music event happening. Plus, with Jacksonville just an hour away, you get small-town charm without sacrificing big-city perks. Whether you’re a history buff, a beach bum, or just someone looking for a laid-back yet vibrant community, St. Augustine is a place that’s hard to resist.

St. Augustine combines historical charm with contemporary living, creating a unique blend.
St. Augustine combines historical charm with contemporary living, creating a unique blend.

5. Greenville, SC

Greenville is one of those places that surprises you—in the best way possible. Tucked in the foothills of the Blue Ridge Mountains, this city has transformed from a quiet textile town into one of the Southeast’s most exciting places to live. Downtown is the heart of it all, with Main Street lined with indie boutiques, top-tier restaurants, and an arts scene that punches way above its weight. And then there’s Falls Park on the Reedy—a stunning urban oasis with waterfalls and a suspension bridge right in the middle of downtown.

Beyond the city, outdoor lovers can escape to Paris Mountain State Park for hiking, biking, and lake views. Plus, Greenville’s economy is booming, with opportunities in tech, healthcare, and manufacturing. It’s small enough to feel like home but big enough to keep things interesting—making it a perfect mix of Southern charm and modern livability.

In discussions about the Southeast's top spots, Greenville frequently emerges as a standout.
In discussions about the Southeast’s top spots, Greenville frequently emerges as a standout.

6. Ocean Springs, MS

Ocean Springs is a coastal escape with a creative soul. This Mississippi town is known for its thriving arts scene, welcoming community, and easy access to the Gulf’s stunning beaches. Strolling through Downtown Ocean Springs, you’ll find independent boutiques, vibrant art galleries, and cafés serving fresh Gulf seafood. The Walter Anderson Museum of Art showcases the area’s deep artistic roots, making it a must-visit for culture lovers.

For those who enjoy the outdoors, Front Beach offers peaceful shoreline views, while the Gulf Islands National Seashore provides opportunities for kayaking, hiking, and birdwatching. Despite its small-town feel, Ocean Springs is just minutes from Biloxi’s entertainment, casinos, and nightlife.

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The cost of living is relatively affordable compared to other beach towns, and the strong sense of community makes it easy to settle in. If you want a relaxed lifestyle with culture, nature, and coastal charm, Ocean Springs is an excellent choice.

If you're looking for a Southeastern haven seamlessly blending artistry, natural beauty, and urban access, Ocean Springs should be on your list.
If you’re looking for a Southeastern haven seamlessly blending artistry, natural beauty, and urban access, Ocean Springs should be on your list.

7. Huntsville, AL

Nicknamed “Rocket City,” Huntsville is where history, innovation, and Southern hospitality come together. The city played a crucial role in the U.S. space program, and you can still see that legacy at the U.S. Space & Rocket Center, one of the top attractions in Alabama.

Beyond its aerospace roots, Huntsville is booming in tech, engineering, and research. The Cummings Research Park—the second-largest in the U.S.—has made the city a hotspot for professionals looking to grow their careers. But it’s not all about work. Outdoor lovers can explore Monte Sano State Park, a local favorite for hiking and mountain biking.

Despite its growth, Huntsville remains affordable, with a lower cost of living than other tech hubs. Whether you’re an engineer, entrepreneur, or just looking for a fresh start, this city offers opportunity without sacrificing quality of life.

For those seeking career growth without sacrificing quality of life, Huntsville is your ideal destination.
For those seeking career growth without sacrificing quality of life, Huntsville is your ideal destination.

8. Charleston, SC

Charleston feels like stepping into a Southern postcard, where cobblestone streets, pastel-colored homes, and centuries-old oak trees create a timeless charm. This historic city blends old-world elegance with modern vibrancy, making it one of the most desirable places to live in the Southeast.

The French Quarter and Battery district offer scenic waterfront views, while King Street is a hub for boutique shopping and award-winning restaurants. The food scene is a standout, from Lowcountry seafood to modern Southern cuisine. If you love history, the city’s well-preserved landmarks, like Fort Sumter and Magnolia Plantation, offer endless discoveries.

Beyond the charm, Charleston boasts a growing economy in tech, healthcare, and tourism. Its strong school system and access to pristine beaches make it ideal for families and professionals alike. With a laid-back coastal vibe and a thriving cultural scene, Charleston is the perfect blend of history, hospitality, and opportunity.

Charleston offers top schools and a thriving job market, making it a best place to live in the Southeast US.
Charleston offers top schools and a thriving job market, making it a best place to live in the Southeast US.

9. Asheville, NC

Set against the backdrop of the Blue Ridge Mountains, Asheville is a city where creativity and nature thrive together. Its downtown pulses with energy, featuring live music, independent bookstores, and farm-to-table dining, while the River Arts District is a hub for local artists and makers.

For outdoor lovers, the Blue Ridge Parkway offers breathtaking drives, scenic hikes, and cascading waterfalls. Pisgah National Forest is perfect for exploring, whether you’re into hiking, fishing, or simply soaking in the mountain air. If craft beer is your thing, Asheville’s thriving brewery scene makes it one of the best beer cities in the country.

With a growing job market in healthcare, tourism, and tech, Asheville provides a balanced lifestyle. Whether you’re drawn by its artistic energy or the call of the mountains, this city offers an unmatched quality of life in the Southeast.

Thinking of living in the Southeast? Asheville makes a compelling argument.
Thinking of living in the Southeast? Asheville makes a compelling argument.

10. St. Petersburg, FL

If there were ever a place where summer never ends, it’s St. Petersburg. With 361 days of sunshine a year, this Gulf Coast city blends laid-back beach vibes with a thriving arts and culture scene. Downtown is packed with energy, from the surreal wonders of the Salvador Dalí Museum to the colorful murals of the Central Arts District.

Outdoor lovers have endless ways to soak up the sun. Paddle through mangroves, bike along the Pinellas Trail, or unwind on St. Pete Beach, one of the best in the country. The Edge District is a hotspot for craft breweries, indie shops, and top-notch dining.

Beyond the fun, St. Pete offers career opportunities in healthcare, marine sciences, and tech, all with a lower cost of living than Miami. If you’re looking for a city that’s both relaxed and exciting, this might just be your perfect match.

St. Pete is a top places to live in the Southeast for your consideration
St. Pete is a top places to live in the Southeast for your consideration
Living in the Southeast, similar to any nation, presents its unique advantages and challenges.
Living in the Southeast, similar to any nation, presents its unique advantages and challenges.
The best places to live in the Southeast for all types of travelers
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Jon Miksis

About Jon Miksis

Award-winning Travel Writer • Founder of Global Viewpoint • 70+ countries visited • 10 Million+ readers

Since 2017, I’ve traveled 3–6 months a year, sharing detailed guides that have helped over 10 million readers travel smarter, deeper, and better. My work blends firsthand experiences — from U.S. road trips and cold-plunge cabins to Michelin-starred dining and business-class flights — with honest, independent reviews.

I’ve been hired by leading tourism boards in 7 countries across Europe, North America, and South America, as well as international travel brands. My travel tips and insights have been featured in Forbes, HuffPost, Yahoo Travel, and The Boston Globe. I’ve personally reviewed 500+ hotels, retreats, and flight experiences — and I never recommend a place I wouldn’t return to myself.

I also save $5–10K per year on airfare using flight tools and 10+ travel credit cards, and I’ve invested over $100K into personal development through transformational retreats and coaching since 2021.

When I’m not road-tripping across the Northeast or writing guides for Global Viewpoint, you’ll find me cold plunging in local lakes, sipping espresso in quiet cafes in Vienna, or chasing fall foliage across New England. I split my time between exploring the world and soaking up life in Boston, my lifelong home base. Some of my favorite places I keep going back to? Switzerland, Spain, Iceland, Italy, Greece, the Faroe Islands, Guatemala, California, Montana, Vermont, and coastal Maine in autumn.

See my latest adventures on Instagram and TikTok.

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